Major Depression
Articles in this topic explain how Major Depression can affect mood, focus, sleep, relationships, medication decisions, and day-to-day care conversations.
What Medication Can and Can’t Do
People come in wanting a pill that fixes their life. They don't say it that way.
Nov 1, 2025
Prozac (Fluoxetine)
Prozac came out in 1987. Almost forty years later it's still on the short list of SSRIs I reach for, and not because of nostalgia.
Oct 20, 2025
Depression Looks Different in Men
Most people think depression looks like sadness... someone crying, withdrawn, hopeless, visibly falling apart.
Oct 19, 2025
Fluvoxamine (Luvox)
Fluvoxamine is the SSRI (selective serotonin reuptake inhibitor, the Zoloft/Lexapro/Prozac class) nobody thinks of first, and that's sort of a shame,…
Sep 9, 2025
Bipolar Disorder, Explained
Bipolar treatment goes wrong in the first appointment more often than in any later one. Get the diagnosis wrong and every prescription after it's wrong.
Aug 27, 2025
Wellbutrin (Bupropion)
Wellbutrin is the weird cousin in the antidepressant family.
Aug 27, 2025
Men’s Health
Men don't usually walk into a psychiatrist's office and say they're depressed.
Aug 20, 2025
Remeron
Remeron is the antidepressant nobody picks first and a lot of guys end up grateful for.
Jul 29, 2025
Men’s Mental Health: Why Asking for Help Feels Impossible
You already know something's off, and you've probably known for a while... months, maybe years.
Jul 1, 2025
Low T vs. Depression: What You Actually Need to Know
Guys come in convinced they have low T when they're actually depressed, and other guys come in convinced they're depressed when their testosterone is in…
Jun 25, 2025
Long-term med use realities (20-year horizons)
The honest answer to "can I stay on this medication for the rest of my life" is: we don't fully know what happens at 30 or 40 years out, because…
Jun 22, 2025
Antidepressant withdrawal vs relapse: distinguishing
Guys stop their antidepressant, feel terrible a couple weeks later, assume the depression is back, restart the medication. Sometimes that's right.
Jun 20, 2025