
Rock bottom is bullshit. The idea that addicts and depressed people have to lose the marriage, lose the job, lose the house, get the DUI, wake up in…
May 6, 2025
Ketamine has been around since 1962, doing its boring day job as an anesthetic in operating rooms and battlefield medic kits, and the depression piece is the much…
May 1, 2025
People sabotage themselves constantly and they can’t tell you why. Get within sight of something working out and they blow it up. Six months sober, the marriage is…
Apr 30, 2025
The IV drip clinic is the chiropractor of the 2020s. Strip-mall storefront, soft lighting, a recliner, a nurse in scrubs, and a thousand-dollar-a-month subscription to feel like you’re…
Apr 29, 2025
Melatonin is one of the most misunderstood things sold in a drugstore, and the misunderstanding got there with help from the supplement industry, the pediatrician’s office, and your…
Apr 26, 2025
Most people who fire their psychiatrist wait about a year too long to do it. They sit through appointment after appointment, refilling something that isn’t quite working, talking…
Apr 25, 2025
Caplyta is the antipsychotic that came out in 2019 and made a bunch of psychiatrists do a double-take at the receptor pharmacology, then another double-take at the price…
Apr 23, 2025
High-dose ketamine done in a clinic is a different animal from the troches you take at home. Same molecule, different dose, different route, and a completely different experience.…
Apr 22, 2025
Lurasidone is the drug you reach for when somebody walks in with bipolar depression and a body that’s already been wrecked by Seroquel. It’s an atypical antipsychotic (the…
Apr 16, 2025
Men’s sexual health is one of those topics where the medicine is mostly straightforward and the conversation is mostly impossible. The biology is well-mapped, the drugs work, the…
Apr 4, 2025