
One of the most powerful ideas that comes up again and again in therapy, and one that Dr. John returns to often on his podcast “The Dr. John…
Jun 11, 2025
Trintellix is the antidepressant pharma reps spent a decade trying to make happen. The generic name is vortioxetine, marketed under Trintellix in the US and Brintellix everywhere else,…
Jun 9, 2025
Addiction is what happens when the brain’s reward wiring gets hijacked. There’s a circuit that’s supposed to push you toward food, sex, novelty, your kid’s face, the things…
May 31, 2025
Finasteride, dutasteride, minoxidil, PRP, microneedling, transplants. The math of male pattern hair loss, the meds that bend it, and the things sold to you that mostly do not.
May 29, 2025
Pristiq is what happens when you take Effexor, skip a metabolic step, and sell it as a new drug. That’s not a dig, that’s the actual mechanism. Venlafaxine…
May 27, 2025
Not every bad day is depression and not every hard week means you need medication. Sometimes life is just difficult, you feel like shit about it, and that’s…
May 21, 2025
You can’t think your way out of being sleep-deprived, you can’t positive-mindset your way through chronic stress, and you can’t meditate away what happens to a brain that’s…
May 18, 2025
Men’s ability to be analytical is a superpower in a lot of ways. It’s what makes you good at solving problems at work, breaking down situations, making decisions…
May 11, 2025
The weight management conversation got rewritten in the last three years and most people still haven’t caught up. The drugs that did the rewriting are GLP-1 agonists. Semaglutide,…
May 9, 2025
“Mood disorder” is a category, not a diagnosis. Under that umbrella sit a half dozen actually-different illnesses: regular old depression, bipolar I, bipolar II, cyclothymia, premenstrual dysphoric disorder,…
May 7, 2025