Factsheet
Everything we have written on Factsheet, in one place.
Ritalin and Methylphenidate
Methylphenidate has been around since 1944 and is still, in 2026, one of the most reliable molecules in psychiatry. Ritalin is the original brand.
Aug 14, 2025
Propranolol
Propranolol is a cardiology drug that wandered into psychiatry by accident and stayed because it does one specific thing well.
Aug 3, 2025
Adderall
Adderall is amphetamine.
Jul 29, 2025
Remeron
Remeron is the antidepressant nobody picks first and a lot of guys end up grateful for.
Jul 29, 2025
Lunesta
Lunesta is the Z-drug you reach for when Ambien isn't holding the night together. Same family, different shape, slightly longer half-life.
Jul 23, 2025
Zoloft
Zoloft is the drug I prescribe more than anything else, and the one patients ask the most questions about before they're willing to swallow the first pill.
Jun 13, 2025
Trintellix (Vortioxetine)
Trintellix is the antidepressant pharma reps spent a decade trying to make happen.
Jun 9, 2025
Pristiq (Desvenlafaxine)
Pristiq is what happens when you take Effexor, skip a metabolic step, and sell it as a new drug. That's not a dig, that's the actual mechanism.
May 27, 2025
Melatonin
Melatonin is one of the most misunderstood things sold in a drugstore, and the misunderstanding got there with help from the supplement industry, the…
Apr 26, 2025
Caplyta (Lumateperone)
Caplyta is the antipsychotic that came out in 2019 and made a bunch of psychiatrists do a double-take at the receptor pharmacology, then another…
Apr 23, 2025
Lurasidone (Latuda)
Lurasidone is the drug you reach for when somebody walks in with bipolar depression and a body that's already been wrecked by Seroquel.
Apr 16, 2025
Gabapentin
Gabapentin is the drug American psychiatry is in a quiet relationship with that nobody really wants to talk about publicly. It's prescribed constantly.
Apr 15, 2025