Topic

Factsheet

Everything we have written on Factsheet, in one place.

Propranolol
Medications · 10 min read

Propranolol

Propranolol is a cardiology drug that wandered into psychiatry by accident and stayed because it does one specific thing well.

Aug 3, 2025
Adderall
Medications · 9 min read

Adderall

Adderall is amphetamine.

Jul 29, 2025
Remeron
Medications · 10 min read

Remeron

Remeron is the antidepressant nobody picks first and a lot of guys end up grateful for.

Jul 29, 2025
Lunesta
Medications · 8 min read

Lunesta

Lunesta is the Z-drug you reach for when Ambien isn't holding the night together. Same family, different shape, slightly longer half-life.

Jul 23, 2025
Zoloft
Medications · 9 min read

Zoloft

Zoloft is the drug I prescribe more than anything else, and the one patients ask the most questions about before they're willing to swallow the first pill.

Jun 13, 2025
Trintellix (Vortioxetine)
Medications · 11 min read

Trintellix (Vortioxetine)

Trintellix is the antidepressant pharma reps spent a decade trying to make happen.

Jun 9, 2025
Pristiq (Desvenlafaxine)
Medications · 9 min read

Pristiq (Desvenlafaxine)

Pristiq is what happens when you take Effexor, skip a metabolic step, and sell it as a new drug. That's not a dig, that's the actual mechanism.

May 27, 2025
Melatonin
Medications · 9 min read

Melatonin

Melatonin is one of the most misunderstood things sold in a drugstore, and the misunderstanding got there with help from the supplement industry, the…

Apr 26, 2025
Caplyta (Lumateperone)
Medications · 9 min read

Caplyta (Lumateperone)

Caplyta is the antipsychotic that came out in 2019 and made a bunch of psychiatrists do a double-take at the receptor pharmacology, then another…

Apr 23, 2025
Lurasidone (Latuda)
Medications · 9 min read

Lurasidone (Latuda)

Lurasidone is the drug you reach for when somebody walks in with bipolar depression and a body that's already been wrecked by Seroquel.

Apr 16, 2025
Gabapentin
Medications · 8 min read

Gabapentin

Gabapentin is the drug American psychiatry is in a quiet relationship with that nobody really wants to talk about publicly. It's prescribed constantly.

Apr 15, 2025
Clonidine
Medications · 8 min read

Clonidine

Clonidine is a blood pressure medication from the 1970s that turned out to be useful for half a dozen things it was never designed for.

Apr 13, 2025