Newest articles
Every article in one chronological feed, newest first. Showing 37-72 of 302 posts.
Trazodone vs Quviviq vs Belsomra
The sleep medication landscape in 2026 is in a weird place. Trazodone is still the default for most prescribers, mostly out of habit and price.
Apr 18, 2026
Benzodiazepine Medications
Benzodiazepines work fast, which is exactly why they need a narrow lane, a clear exit plan, and more respect than casual anxiety prescribing usually gives them.
Apr 16, 2026
Ozempic, GLP-1s, and mood
The GLP-1 agonists (Ozempic and Wegovy and Mounjaro and the rest, a class of medications originally developed for type 2 diabetes and now used…
Apr 16, 2026
Buprenorphine for depression and chronic pain
Buprenorphine is best known as an addiction medication, particularly for opioid use disorder, but a growing body of research and a quieter clinical…
Apr 14, 2026
Stimulant Medications
Stimulants can be life-changing for ADHD and narcolepsy, but the Schedule II, diversion, sleep, blood pressure, appetite, and misuse conversations aren't optional.
Apr 14, 2026
Pharmacogenomic testing for psych meds
GeneSight and the other pharmacogenomic tests (cheek-swab panels that look at your liver-enzyme genetics to suggest which psych medications you'll handle…
Apr 12, 2026
Caplyta off-label use
Caplyta (lumateperone) is one of the newer atypical antipsychotics, FDA-approved for schizophrenia and bipolar depression, and what's more interesting…
Apr 10, 2026
Vraylar for depression augmentation
Vraylar (cariprazine) is an atypical antipsychotic that got an FDA add-on indication for major depression a few years back.
Apr 8, 2026
Insomnia, Explained
Insomnia treatment is where people learn the hard way that exhaustion and sleep aren't the same thing.
Apr 6, 2026
Auvelity (dextromethorphan/bupropion)
Auvelity is a once-daily pill that combines dextromethorphan, the cough syrup ingredient, with bupropion, which most people know as Wellbutrin.
Apr 6, 2026
Social Anxiety, Explained
A practical guide to social anxiety treatment: CBT, exposure, medication, safety behaviors, and how recovery actually gets built.
Apr 3, 2026
Doxepin for sleep
Doxepin is a tricyclic antidepressant from the 1960s that turned out, at very low doses, to be one of the best sleep medications available.
Apr 2, 2026
Panic Treatment
A practical guide to treating panic disorder with CBT, interoceptive exposure, medication, and fewer rescue rituals.
Apr 1, 2026
Pregabalin (Lyrica)
Pregabalin is gabapentin's better-looking, more expensive cousin.
Mar 31, 2026
OCD Treatment
A practical guide to OCD treatment, exposure and response prevention, medication, reassurance traps, and when to get specialty care.
Mar 29, 2026
Vivitrol (extended-release naltrexone)
Vivitrol is naltrexone in a syringe, given once a month in your butt. That's the whole pitch.
Mar 28, 2026
Naltrexone for alcohol
Naltrexone is the medication that gets prescribed more than any other for alcohol use disorder in clinics that actually know what they're doing, and it is…
Mar 26, 2026
Prescription Education: Know What’s Actually in That Bottle
Most med checks hand you a script and skip the useful part. You still need to know the name, dose, timeline, side effects, generic issues, taper rules, and when to…
Mar 26, 2026
Seroquel (quetiapine)
Seroquel is the antipsychotic that gets prescribed for everything other than what it's actually approved for, and the off-label sleep use is the biggest…
Mar 24, 2026
Statins
Statins cut events when the risk is real. The decision should come from your risk numbers and the side effects you can actually live with, not vibes.
Mar 24, 2026
Microdosing: what controlled trials actually show
The honest answer on microdosing is that the controlled trials don't show much, the open-label data shows a lot, and the difference between those two…
Mar 22, 2026
Ibogaine: Real Promise, Real Risk
Ibogaine might be the strangest substance in the whole psychedelic treatment conversation, because the promise is real and the risk is real and they sit…
Mar 21, 2026
Online ADHD clinics & the regulatory crackdown
Done and Cerebral are the two names everybody remembers from the great pandemic ADHD telehealth boom, and the story of what happened to them is most of…
Mar 20, 2026
Ayahuasca for Depression: Promising, Strange, and Still Early
Ayahuasca has a real but early depression signal. The hard part is separating clinical research from retreat hype and real safety risk.
Mar 18, 2026
Dextromethorphan for Depression: The Legal, Overlooked One
Dextromethorphan’s the weird one in this whole conversation because unlike MDMA or psilocybin or ayahuasca, it isn’t hiding behind a Schedule I wall. It’s been sitting on pharmacy…
Mar 16, 2026
TMS (Transcranial Magnetic Stimulation)
TMS (transcranial magnetic stimulation, an in-office procedure where a magnetic coil sits against the side of your head and pulses a magnetic field into a…
Mar 16, 2026
EMDR
EMDR stands for eye movement desensitization and reprocessing, which is a mouthful and also kind of misleading because the eye movements may not actually…
Mar 14, 2026
Is my penis normal?
Most guys who worry they're too small aren't actually too small, they're comparing themselves to porn, bad angles, lies, memory, locker room mythology,…
Mar 13, 2026
Suboxone (buprenorphine/naloxone)
Suboxone is the closest thing we have to a miracle drug in psychiatry, and most of the people who need it spent years being talked out of taking it by…
Mar 12, 2026
Kegels: when they help and when they backfire
A lot of men hear pelvic floor and immediately think kegels, which is how this whole topic gets dumbed down fast, because the pelvic floor is a real…
Mar 11, 2026
Abilify (aripiprazole)
Abilify is the drug I add to an antidepressant when the antidepressant is doing maybe sixty percent of the job and we need to find the other forty.
Mar 10, 2026
Lamictal (lamotrigine)
Lamictal is one of those medications I actually like prescribing, which isn't a sentence I get to write very often in psychiatry.
Mar 8, 2026
Weed and Your Sex Life: The Honest Read
Weed and sex isn't a simple good or bad story. Acute use may help some people, chronic use can start costing you, and the evidence is mixed.
Mar 8, 2026
Lithium
Lithium is the best mood stabilizer we have for bipolar I, and we don't use it nearly enough. That's the whole post, more or less. The rest is detail.
Mar 6, 2026
Stress, Cortisol, and a Flat Sex Life
Stress can flatten desire and wreck erections, but the clean cortisol story is usually too neat. What stress actually does to libido and performance.
Mar 5, 2026
Klonopin (Clonazepam)
The pitch for Klonopin, the one I hear from prescribers and from the guys who've been on it for years, is that it's the cleaner benzo.
Mar 4, 2026