Tricyclic Antidepressant
Articles tagged Tricyclic Antidepressant cover when this care approach may fit, what to expect, tradeoffs, safety questions, and how it can connect with therapy, medication, or lifestyle work.
Tricyclic Antidepressants
Tricyclics are older antidepressants that can still help depression, pain, migraine, and sleep, but overdose risk and anticholinergic side effects keep them out of the casual lane.
May 20, 2026
Desipramine (Norpramin)
Desipramine is an older norepinephrine-leaning tricyclic. It can still work, but it asks for more side-effect and safety respect.
Dec 14, 2025
Clomipramine (Anafranil)
Clomipramine is an older TCA for OCD that can hit hard when SSRIs fall short, but side effects, safety rules, and follow-up matter.
Dec 12, 2025
Imipramine (Tofranil)
Imipramine is an old tricyclic that can help depression and panic, but the burden is harder to justify when cleaner options fit.
Dec 9, 2025
Nortriptyline (Pamelor)
Nortriptyline is an older tricyclic that still does real work without feeling as blunt as amitriptyline for some patients.
Dec 7, 2025
Amitriptyline (Elavil)
Amitriptyline is an older medication that still hangs around because it does several useful things at once, not because it's clean.
Dec 4, 2025