
Remeron is the antidepressant nobody picks first and a lot of guys end up grateful for. The generic name is mirtazapine, it’s been around since the mid-90s, and…
Jul 29, 2025
PTSD is what happens when your brain encodes a memory wrong. Most memories get filed away, lose their sharp edges, and when you pull them back out a…
Jul 19, 2025
Ketamine-assisted therapy is what it sounds like. You take ketamine in a clinical setting, and you have a therapist actually present (or involved in close follow-up afterward) to…
Jul 6, 2025
You already know something’s off, and you’ve probably known for a while… months, maybe years. The sleep’s gone sideways, the temper’s shorter than it should be, you’re going…
Jul 1, 2025
Depression ≠ sadness. Sadness has a thing it’s about. Depression doesn’t, it just follows you around like a Dementor sucking the light out of the world. The texts…
Jun 19, 2025
Zoloft is the drug I prescribe more than anything else, and the one patients ask the most questions about before they’re willing to swallow the first pill. Sertraline…
Jun 12, 2025
Trintellix is the antidepressant pharma reps spent a decade trying to make happen. The generic name is vortioxetine, marketed under Trintellix in the US and Brintellix everywhere else,…
Jun 9, 2025
Addiction is what happens when the brain’s reward wiring gets hijacked. There’s a circuit that’s supposed to push you toward food, sex, novelty, your kid’s face, the things…
May 31, 2025
Pristiq is what happens when you take Effexor, skip a metabolic step, and sell it as a new drug. That’s not a dig, that’s the actual mechanism. Venlafaxine…
May 27, 2025
Not every bad day is depression and not every hard week means you need medication. Sometimes life is just difficult, you feel like shit about it, and that’s…
May 21, 2025