Patients
Everything we have written on Patients, in one place.
Spravato (esketamine) protocol
Spravato is FDA-approved esketamine, given as a nasal spray under direct supervision in a certified clinic.
Apr 4, 2026
Doxepin for sleep
Doxepin is a tricyclic antidepressant from the 1960s that turned out, at very low doses, to be one of the best sleep medications available.
Apr 2, 2026
Pregabalin (Lyrica)
Pregabalin is gabapentin's better-looking, more expensive cousin.
Mar 31, 2026
Vivitrol (extended-release naltrexone)
Vivitrol is naltrexone in a syringe, given once a month in your butt. That's the whole pitch.
Mar 28, 2026
Naltrexone for alcohol
Naltrexone is the medication that gets prescribed more than any other for alcohol use disorder in clinics that actually know what they're doing, and it's…
Mar 26, 2026
Seroquel (quetiapine)
Seroquel is the antipsychotic that gets prescribed for everything other than what it's actually approved for, and the off-label sleep use is the biggest…
Mar 24, 2026
Microdosing: what controlled trials actually show
The honest answer on microdosing is that the controlled trials don't show much, the open-label data shows a lot, and the difference between those two…
Mar 22, 2026
Online ADHD clinics & the regulatory crackdown
Done and Cerebral are the two names everybody remembers from the great pandemic ADHD telehealth boom, and the story of what happened to them is most of…
Mar 20, 2026
Ketamine clinics: legit vs sketchy
The ketamine clinic boom of the last five years is two different things wearing one storefront.
Mar 18, 2026
TMS (Transcranial Magnetic Stimulation)
TMS (transcranial magnetic stimulation, an in-office procedure where a magnetic coil sits against the side of your head and pulses a magnetic field into a…
Mar 16, 2026
EMDR
EMDR stands for eye movement desensitization and reprocessing, which is a mouthful and also kind of misleading because the eye movements may not actually…
Mar 14, 2026
Suboxone (buprenorphine/naloxone)
Suboxone is the closest thing we have to a miracle drug in psychiatry, and most of the people who need it spent years being talked out of taking it by…
Mar 12, 2026