Ketamine clinics: legit vs grift
The ketamine clinic boom of the last five years is two different things wearing one storefront. One is a real treatment with real data for the kind of…
Jun 1, 2026
Klonopin (Clonazepam)
The pitch for Klonopin, the one I hear from prescribers and from the guys who’ve been on it for years, is that it’s the cleaner benzo. Longer half-life,…
Jun 1, 2026
Lamictal (lamotrigine)
Lamictal is one of those medications I actually like prescribing, which is not a sentence I get to write very often in psychiatry. The people on it tend…
Jun 1, 2026
Lithium
Lithium is the best mood stabilizer we have for bipolar I, and we don’t use it nearly enough. That’s the whole post, more or less. The rest is…
Jun 1, 2026
MAT (Medication-Assisted Treatment) full landscape
If you have opioid use disorder, medication is the actual treatment. Not therapy first, not 12-step first, not the white-knuckle abstinence approach that’s been the default for forty…
Jun 1, 2026
Microdosing: what controlled trials actually show
The honest answer on microdosing is that the controlled trials don’t show much, the open-label data shows a lot, and the difference between those two things is mostly…
Jun 1, 2026
Naltrexone for alcohol
Naltrexone is the medication that gets prescribed more than any other for alcohol use disorder in clinics that actually know what they’re doing, and it’s the one most…
Jun 1, 2026
Online ADHD clinics & the regulatory crackdown
Done and Cerebral are the two names everybody remembers from the great pandemic ADHD telehealth boom, and the story of what happened to them is most of the…
Jun 1, 2026
Ozempic, GLP-1s, and mood
The GLP-1 agonists (Ozempic and Wegovy and Mounjaro and the rest, a class of medications originally developed for type 2 diabetes and now used aggressively for weight loss)…
Jun 1, 2026
Pharmacogenomic testing for psych meds
GeneSight and the other pharmacogenomic tests (cheek-swab panels that look at your liver-enzyme genetics to suggest which psych medications you’ll handle well or badly) promise that a single…
Jun 1, 2026